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pentobarbital will reduce the level or result of buprenorphine, prolonged-acting injection by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Sufferers who transfer to buprenorphine extended-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers must be monitored to ensure bup